CJC-1295

The GHRH Analogue

Comprehensive evidence-based information on growth hormone optimization and anti-aging

Primary Benefit

Growth Hormone Release

Administration

Injectable

Status

Research Peptide

Clinical Insights

Evidence-based analysis from Dr. Jobby John, PharmD, FACA

Provider Access

What is CJC-1295?

CJC-1295 is a synthetic growth hormone-releasing hormone (GHRH) analog that stimulates the natural production of growth hormone from the pituitary gland. With a half-life of 6-8 days, it provides sustained growth hormone elevation leading to enhanced muscle growth, fat loss, improved recovery, and anti-aging benefits.

GHRH Analog

CJC-1295 is designed to mimic natural growth hormone-releasing hormone (GHRH) with an extended half-life.

Pituitary Signal

It sends sustained signals to the pituitary gland to naturally increase growth hormone production and IGF-1 levels.

Research and Potential Benefits

CJC-1295 significantly enhances muscle protein synthesis and recovery through sustained growth hormone elevation.

  • Increases Muscle Mass: Stimulates protein synthesis leading to lean muscle growth and strength gains.
  • Faster Recovery: Accelerates tissue repair and reduces recovery time between workouts.
  • Increased IGF-1: Elevates IGF-1 levels by up to 80% for enhanced anabolic effects.

CJC-1295 promotes fat loss and provides anti-aging benefits through sustained growth hormone elevation.

  • Reduces Body Fat: Promotes lipolysis leading to significant reductions in body fat percentage.
  • Improves Skin Quality: Increases collagen production for better skin elasticity and reduced wrinkles.
  • Enhanced Sleep: Improves sleep quality and promotes deeper, more restorative sleep cycles.

As a research peptide, CJC-1295 has been studied in clinical trials with a relatively favorable safety profile, but requires medical supervision.

  • ! Research Use Only: Not FDA-approved for human use; available only through compounding pharmacies for research purposes.
  • ! Common Side Effects: Injection site reactions, headache, flushing, and transient increases in heart rate.
  • ! Contraindications: Avoid in patients with active cancer, severe heart disease, or hypersensitivity to growth hormone.

References & Citations

  1. Teichman, S. L., et al. (2006). Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab.
  2. Ionescu, M., & Frohman, L. A. (2006). Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab.
Dr. Jobby John

Ask Dr. John About CJC-1295

Get personalized clinical insights from Dr. Jobby John, PharmD, FACA. Ask specific questions about CJC-1295 and receive evidence-based answers from his extensive clinical experience.

Ask about dosing, side effects, patient selection, monitoring, contraindications, or clinical experience

HIPAA-compliant responses

Common Questions About CJC-1295